Syntheses, spectral characterization and antidiabetic activities of oxidovanadium(V) complexes with bi-and tridentate ligands
By: Patel, Neetu
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Contributor(s): Patel, A. K.
Publisher: New Delhi CSIR 2022Edition: Vol.61(3), Mar.Description: 254-262p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: Four new oxidovanadium(V) complexes [VO(L1)(Mol)] (1), [VO(L2)(Mol)] (2), [VO(L3)(Mol)] (3) and [VO(L4)(Mol)] (4) (where L1-L4 = aroylhydrazones and Mol = maltol) have been synthesized with different ligands. The complexes have been characterized using microanalysis, spectral fab mass, UV-visible, electrochemical (cyclic voltammetry and differential pulse voltammetry), density functional theory calculations have been performed to predict the optimized geometry, global reactivity parameters and electron density. In these complexes, the d-d absorption band is not observed as being d0 vanadium centres in these complexes. The electrochemical behaviour of these complexes are explored by cyclic voltammetry and differential pulse voltammetry (DPV). All complexes exhibit one electron transfer i.e., reduction of vanadium(V) to vanadium(IV). These complexes are screened for in vitro α-glucosidase and α-amylase inhibition study. Complex 3 has an interesting insulin-like activity.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2023-0710 |
Four new oxidovanadium(V) complexes [VO(L1)(Mol)] (1), [VO(L2)(Mol)] (2), [VO(L3)(Mol)] (3) and [VO(L4)(Mol)] (4) (where L1-L4 = aroylhydrazones and Mol = maltol) have been synthesized with different ligands. The complexes have been characterized using microanalysis, spectral fab mass, UV-visible, electrochemical (cyclic voltammetry and differential pulse voltammetry), density functional theory calculations have been performed to predict the optimized geometry, global reactivity parameters and electron density. In these complexes, the d-d absorption band is not observed as being d0 vanadium centres in these complexes. The electrochemical behaviour of these complexes are explored by cyclic voltammetry and differential pulse voltammetry (DPV). All complexes exhibit one electron transfer i.e., reduction of vanadium(V) to vanadium(IV). These complexes are screened for in vitro α-glucosidase and α-amylase inhibition study. Complex 3 has an interesting insulin-like activity.
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